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Sigma Aldrich C5 Lenalidomide

Catalog No. 911690100MG Shop All MilliporeSigma Sigma Organic Chemistry Products
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91-169-0100MG 100 mg
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Description

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

C5 Lenalidomide is a derivative of the Cereblon (CRBN)-binding ligand lenalidomide, which possesses an amine at the C4 position. C5 Lenalidomide can be used to bind the CRBN E3 ubiquitin ligase in targeted protein degradation research or in the synthesis of protein degraders with a C5 exit vector. Learn more about proteolysis-targeting chimeras (PROTACs) and the building blocks to design them in our Technology Spotlight: Degrader Building Blocks for Targeted Protein DegradationTechnology Spotlight: Degrader Building Blocks for Targeted Protein DegradationPortal: Building PROTAC™ Degraders for Targeted Protein DegradationAmino-substituted thalidomide analogs: potent inhibitors of TNF-alpha productionTargeted Protein Degradation by Small MoleculesPROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

Specifications

CAS 2361138-33-0
Molecular Formula C22H20ClNO3
Linear Formula C22H20ClNO3
Quantity 100 mg
Synonym N-Benzyl-2-chloro-N-(4-(4-methoxyphenoxy)phenyl)acetamide; E3 ubiquitin ligase ligand; Ligand for PROTAC(R)-ßresearch; RNF4-targeting ligand
Molecular Weight (g/mol) 381.85 g/mol
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