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Enzo Life Sciences C6 Ceramide, (5mg), CAS Number: 124753-97-5
Supplier: Enzo Life Sciences BMLSL1100005
Cell-permeable ceramide analog. A biologically active, cell-permeable, but nonphysiologic ceramide analog. It activates protein phosphatase 2A and MAP kinase (MAPK/ERK), suppresses insulin-induced tyrosine phosphorylation and inhibits glycoprotein traffic by the secretory pathway. It inhibits diacylglycerol accumulation and phospholipase D activation in fibroblasts. It induces an arrest at the G0/G1 transition of the cell cycle (10μM) and causes apoptosis (15μM or greater) in Molt-4 leukemia cells. Alternative Name: N-Hexanoyl-D-erythro-sphingosine. Formula: C24H47NO3. MW: 397.7. CAS Number: 124753-97-5. Purity: ≥98% (TLC). Appearance: White waxy solid. Solubility: Soluble in 100% ethanol (>25mg/ml) and DMSO (>50mg/ml). Use/Stability: Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C. Long Term Storage: -20°C
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