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AdipoGen C75

Supplier: AdipoGen AGCR12904M005

Chemical. CAS 191282-48-1. Formula C14H22O4. MW 254.3. . Stable synthetic cerulenin derivative. Competitive irreversible fatty acid synthase FASN inhibitor that acts on KR, ACP and TE domains. Used to study fatty acid synthesis in metabolic disorders and cancer. Useful agent for immunometabolism research. Anorexigenic agent, activating CPT1 to accelerate fatty acid beta-oxidation. Shown to inhibit food intake through AMPK-related pathways. Cytotoxic to many cancer cell lines. Antitumor agent shown to suppress DNA replication and induce apoptosis.
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