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Enzo Life Sciences C75 (1mg). CAS: 191282-48-1
Supplier: Enzo Life Sciences ALX270286M001
Inhibitor of fatty acid synthase (FAS) reducing food intake and body weight in mice. Exhibits irreversible slow-binding biphasic inactivation of fatty acid synthase. Downregulates neuropeptide Y and Agouti-related protein expression. Has been proposed to activate CPT-1 activity in liver and adipose tissue, leading to increased fatty acid oxidation and energy production. Shows significant in vivo antitumor activity in human breast cancer cells. Suppresses DNA replication and induces apoptosis. FAS inhibition by C75 leads to a dramatic accumulation of the CDK inhibitor p27KIP1 from cytosol to cell nuclei. Alternative name: trans-4-Carboxy-5-octyl-3-methylene-butyrolactone. Formula: C14H22O4. MW: 254.3. Purity: ≥98%. Solubility: Soluble in dichloromethane, methanol or DMSO. Long Term Storage: -20°C.
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