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Cayman Chemical C8 CeramIde-mPEG 2000 1mg
Supplier: Cayman Chemical 419541 MG
A PEGylated form of C8 ceramide; has been used in the generation of lipoplexes and lipid particles for the delivery of plasmid DNA and siRNA in vitro and in vivo; lipid particles encapsulating plasmid DNA and containing C8 MPEG(2000) ceramide have a higher transfection efficiency than those containing C14- or C20 MPEG(2000) ceramide in BHK cells; lipoplexes containing C8 MPEG(2000) ceramide and encapsulating siRNAs targeting HPV E7 peptide and Mcl-1 induce apoptosis in Ca Ski and SiHa cervical cancer cells; intravaginal administration of lipoplexes containing C8 MPEG(2000) ceramide accumulate in vaginal tissue in mice
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