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Apexbio Technology LLC CA 074 134448-10-5 10mg
Supplier: Apexbio Technology LLC A192610
CA 074 (CAS 134448-10-5) is a selective inhibitor of cathepsin B a cysteine protease involved in diverse pathological mechanisms By targeting cathepsin B CA 074 alleviates neurotoxicity induced by amyloid-activated microglia and inhibits proteolytic cascades associated with cell growth suppression and plasminogen activation Additionally CA 074 treatment modulates immune responses by shifting CD4 T cells from a Th2 to a Th1 phenotype reducing IgE and IgG1 levels In vivo studies indicate that CA 074 can attenuate TNF- -induced hepatic injury highlighting its relevance as a research tool in inflammation immunology and neurodegenerative disease investigations
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