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Medchemexpress LLC CA-5f | 1370032-19-1 | 99.1% | 388.46 | 50 MG
SDP

Catalog No. 5000437770
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CA-5f is a potent late-stage macroautophagy/autophagy inhibitor that works by inhibiting autophagosome-lysosome fusion. It increases LC3B-II (a marker for monitoring autophagy) and SQSTM1 protein levels, and also increases ROS production. CA-5f exhibits anti-tumor activity. It is for research use only and not sold to patients.

  • Potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion.
  • Increases LC3B-II and SQSTM1 protein levels.
  • Increases ROS production.
  • Exhibits anti-tumor activity.
  • Inhibits the growth of A549 cells and is less cytotoxic to normal HUVECs.
  • Well tolerated and potently inhibits tumor growth in nude mice bearing A549 lung cancer cells.
  • Suppresses autophagic flux and induces apoptosis in nude mice bearing A549 lung cancer cells.

Catalog No. 50-004-37770 Supplier Medchemexpress LLC Supplier No. HY11269850MG
May include imposed supplier surcharges.
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CA-5f is a potent late-stage macroautophagy/autophagy inhibitor that works by inhibiting autophagosome-lysosome fusion. It increases LC3B-II (a marker for monitoring autophagy) and SQSTM1 protein levels, and also increases ROS production. CA-5f exhibits anti-tumor activity. It is for research use only and not sold to patients.

  • Potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion.
  • Increases LC3B-II and SQSTM1 protein levels.
  • Increases ROS production.
  • Exhibits anti-tumor activity.
  • Inhibits the growth of A549 cells and is less cytotoxic to normal HUVECs.
  • Well tolerated and potently inhibits tumor growth in nude mice bearing A549 lung cancer cells.
  • Suppresses autophagic flux and induces apoptosis in nude mice bearing A549 lung cancer cells.

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