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AdipoGen Cabozantinib S-malate (1 g)
Supplier: AdipoGen CDXC0698G001
Chemical. CAS: 1140909-48-3. Formula: C32H30FN3O10. MW: 635.59. The s-malate salt form of Cabozantinib is very potent orally available inhibitor of multiple receptor tyrosine kinases (RTK), specifically MET and VEGFR2. It also inhibits KIT, FLT3, Tie-2, RET and AXL. Cabozantinib shows dose-dependent inhibition of tumor growth and tumor regression, associated with disruption of the tumor vasculature, angiogenesis and extensive tumor cell apoptosis.
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