MilliporeSigma™ Calbiochem™ 1-Aminocyclopropane-1-carboxylic Acid
An agonist for the glycine modulatory site of the N-methyl-D-aspartate (NMDA) receptor complex.
Manufacturer: MilliporeSigma™ 1491011GM
DescriptionAn agonist for the glycine modulatory site of the N-methyl-D-aspartate (NMDA) receptor complex. Mimics the effects of glycine on the NMDA receptor ion channel and blocks 3H-glycine binding to rat forebrain membrane (IC50 = 38 nM). Blocks NMDA-induced release of arachidonic acid (IC50 = 131μM) in cerebellar granule cells. Reduces NMDA-induced cell death in hippocampal neurons.
|98% by TLC|
|Glycine modulatory site of the N-methyl-D-aspartate (NMDA) receptor complex|
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