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MilliporeSigma™ Calbiochem™ 3,4-Dichloroisocoumarin

A potent irreversible inhibitor of serine proteases

Manufacturer:  MilliporeSigma™ 28781510MG

Catalog No. 28-781-510MG


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Description

Description

A potent irreversible inhibitor of serine proteases. Blocks apoptotic internucleosomal DNA cleavage in thymocytes without the involvement of endonucleases. Reacts with serine proteases to release an acylchloride moiety that can acylate another active site residue. Does not affect thiol proteases and metalloproteases. Also has no activity towards β-lactamases. Effective at concentrations ranging from 5-100µM.
Specifications

Specifications

99% by elemental analysis
Protect from Moisture
serine proteases
C9H4Cl2O2
DMF or DMSO
White lyophilized solid
10mg
51050-59-0
215g/mol
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