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MilliporeSigma™ Calbiochem™ 3,4-Dichloroisocoumarin

Catalog No. 28781510MG Shop All MilliporeSigma Products
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28-781-510MG 10 mg
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Description

A potent irreversible inhibitor of serine proteases

A potent irreversible inhibitor of serine proteases. Blocks apoptotic internucleosomal DNA cleavage in thymocytes without the involvement of endonucleases. Reacts with serine proteases to release an acylchloride moiety that can acylate another active site residue. Does not affect thiol proteases and metalloproteases. Also has no activity towards β-lactamases. Effective at concentrations ranging from 5-100μM.
TRUSTED_SUSTAINABILITY

Specifications

Color White
Description 99% by elemental analysis
Target Proteins serine proteases
CAS 51050-59-0
Molecular Formula C9H4Cl2O2
Formula Weight 215g/mol
Solubility DMF or DMSO
Content And Storage Protect from moisture
Form Lyophilized
Quantity 10 mg
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