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MilliporeSigma™ Calbiochem™ 4-Hydroxynonenal

Catalog No. 3932041MG Shop All MilliporeSigma Products
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1 mg

Catalog No. 39-320-41MG

Supplier: MilliporeSigma™ 3932041MG

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Description

4-Hydroxynonenal, CAS 75899-68-2, is a major aldehyde product formed by peroxidation of ω-6-unsaturated fatty acids that is regarded as a specific marker of lipid peroxidation.

A major aldehyde product formed by peroxidation of ω-6-unsaturated fatty acids that is regarded as a specific marker of lipid peroxidation. Inhibits proliferation and induces differentiation of HL-60 human leukemic cells. Also induces cell death in murine alveolar macrophages and in PC12 cells. An inhibitor of state 3 respiration at micromolar levels. Causes a transient increase in cytosolic Ca2+ and irreversibly inhibits Na+, K+-ATPase activity (IC50 = 120μM). Acts as a reversible inhibitor of c-Jun N-terminal kinase (JNK).
TRUSTED_SUSTAINABILITY

Specifications

Formulation Supplied at 10mg/mL in ethanol
Description 98% by HPLC
Target Proteins Na+, K+-ATPase activity
CAS 75899-68-2
Molecular Formula C9H16O2
Formula Weight 156.2g/mol
Form Liquid
Quantity 1 mg
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