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  6. 28789150MG

MilliporeSigma™ Calbiochem™ 5,6-Dichloro-1-β-D-ribofuranosylbenzimidazole

Catalog No. 28789150MG
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Quantity:
50 mg

Description

A potent, ATP-competitive, and specific inhibitor of casein kinase II (IC50 = 6 μM).

A potent, ATP-competitive, and specific inhibitor of casein kinase II (IC50 = 6μM). Reported to inhibit insulin-stimulated nuclear and cytosolic p70S6 kinase in CHO cells. Accentuates premature termination of transcription. Has been used to inhibit RNA polymerase II transcription which may be dependent on casein kinase II. Inhibits germinal vesicle breakdown in bovine oocytes. Induces G1/S cell cycle arrest.
TRUSTED_SUSTAINABILITY

Specifications

Color White
Description 98% by TLC
Target Proteins casein kinase II
CAS 53-85-0
Molecular Formula C12H12Cl2N2O4
Formula Weight 319.2g/mol
Solubility DMSO or EtOH
Form Solid
Quantity 50 mg
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