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MilliporeSigma™ Calbiochem™ Adenophostin A, Hexasodium Salt
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Quantity:
50 μg
Description
One of the most potent known agonist of type 1 inositol 1,4,5-trisphosphate receptor (InsP3R; EC50 = 10.9nM). Exhibits about 50- to 100-fold greater affinity for IP3R than IP3. Stimulates Ca2+ release from Ins(1,4,5)P3-sensitive Ca2+ stores in microsomal preparations, permeabilized cells, and lipid vesicles containing purified InsP3R (EC50 = 14.7nM for Ca2+ release from permeabilized hepatocytes). Does not bind to Ins(1,3,4,5)P4 binding sites and is resistant to enzymatic degradation.
Specifications
Specifications
| Color | White |
| Description | 90% by HPLC |
| Target Proteins | Type 1 inositol 1,4,5-trisphosphate receptor (InsP3R) |
| Molecular Formula | C16H20N5O18P3·6Na |
| Formula Weight | 801.2g/mol |
| Solubility | H2O |
| Content And Storage | Hygroscopic |
| Form | Solid |
| Quantity | 50 μg |
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