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MilliporeSigma™ Calbiochem™ Adenophostin A, Hexasodium Salt

Catalog No. 11550050UG Shop All MilliporeSigma Products
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Quantity:
50 μg

Adenophostin A, Hexasodium Salt, is a potent agonist of type 1 inositol 1,4,5-trisphosphate receptor (InsP3R; EC50 = 10.9nM). Exhibits about 50- to 100-fold greater affinity for IP3R than IP3.

One of the most potent known agonist of type 1 inositol 1,4,5-trisphosphate receptor (InsP3R; EC50 = 10.9nM). Exhibits about 50- to 100-fold greater affinity for IP3R than IP3. Stimulates Ca2+ release from Ins(1,4,5)P3-sensitive Ca2+ stores in microsomal preparations, permeabilized cells, and lipid vesicles containing purified InsP3R (EC50 = 14.7nM for Ca2+ release from permeabilized hepatocytes). Does not bind to Ins(1,3,4,5)P4 binding sites and is resistant to enzymatic degradation.
TRUSTED_SUSTAINABILITY

Specifications

Color White
Description 90% by HPLC
Target Proteins Type 1 inositol 1,4,5-trisphosphate receptor (InsP3R)
Molecular Formula C16H20N5O18P3·6Na
Formula Weight 801.2g/mol
Solubility H2O
Content And Storage Hygroscopic
Form Solid
Quantity 50 μg
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