Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Protein Purification
  5. Protease Inhibitors and Phosphatase Inhibitors
  6. 5058550001

MilliporeSigma™ Calbiochem™ Adenovirus Proteinase Inhibitor, NSC 37249

Catalog No. 5058550001 Shop All MilliporeSigma Products
Change view
Click to view available options
Quantity:
10 mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
50-585-50001 10 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. 50-585-50001 Supplier MilliporeSigma™ Supplier No. 5058550001
Only null left
Add to Cart
Add to Cart

Description

An inhibitor of adenovirus cysteine proteinase AVP that simultaneously targets AVP co-factor pVIc N-terminal binding pocket (K

A sulfonyldiphenylene- bis -dicyclohexylaminoacetamide compound that acts as a potent and selective inhibitor against adenovirus cysteine proteinase AVP by targeting simultaneously AVP co-factor pVIc (GVQSLKRRRCF) N-terminal binding pocket ( K i = 150nM) and AVP-pVIc substrate-binding site ( K i = 400nM), blocking both AVP-pVIc active complex formation (IC50 = 140nM; [substrate] = 5μM & [pVIc] = 40μM) and catalytic activity (IC50 = 490nM; [substrate] = 5μM) without affecting trypsin or papain protease activity even at concentrations as high as 10μM.
TRUSTED_SUSTAINABILITY

Specifications

Color Off-white
Description 90% by HPLC
Target Proteins AVP co-factor pVIc (GVQSLKRRRCF) N-terminal binding pocket
Molecular Formula C40H58N4O4S
Solubility 5% TFA in EtOH
Content And Storage Protect from light
Form Powder
Quantity 10 mg
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.