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MilliporeSigma™ Calbiochem™ AG 1295

Catalog No. 6585505MG Shop All MilliporeSigma Products
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Description

A cell-permeable, reversible, ATP-competitive, and selective inhibitor of platelet-derived growth factor (PDGF) receptor kinase (IC50 = 500nM) and PDGF-dependent DNA synthesis (IC50 = 2.5μM) in Swiss/3T3 cells.

A cell-permeable, reversible, ATP-competitive, and selective inhibitor of platelet-derived growth factor (PDGF) receptor kinase (IC50 = 500nM) and PDGF-dependent DNA synthesis (IC50 = 2.5μM) in Swiss/3T3 cells. Has no effect on EGF receptor autophosphorylation and shows only a weak effect on EGF- or insulin-stimulated DNA synthesis. A potent blocker of smooth muscle cell proliferation.
TRUSTED_SUSTAINABILITY

Specifications

Color White
Description 95% by HPLC
Target Proteins PDGFR kinase
CAS 71897-07-9
Molecular Formula C16H14N2
Formula Weight 234.3g/mol
Solubility DMSO or CH2Cl2
Content And Storage Protect from light
Form Solid
Quantity 5 mg
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