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  6. MilliporeSigma™ Calbiochem™ Phenylmethylsulfonyl Fluoride

MilliporeSigma™ Calbiochem™ Phenylmethylsulfonyl Fluoride

Catalog No. 523325GM Shop All MilliporeSigma Products
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52-332-5GM 5 g
52-332-1GM 1 g
52-332-25GM 25 g
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Catalog No. 52-332-5GM Supplier MilliporeSigma™ Supplier No. 523325GM
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Description

Phenylmethylsulfonyl Fluoride, CAS 329-98-6, is an irreversible inhibitor of serine proteases. It causes sulfonylation of the active-site serine residues.

Irreversible inhibitor of serine proteases. Its mechanism of action is analogous to that of diisopropylfluorophosphate. PMSF causes sulfonylation of the active-site serine residues. Also reported to inhibit internucleosomal DNA fragmentation in immature thymocytes. For a related, more stable inhibitor, see AEBSF (Cat. No. 101500).
TRUSTED_SUSTAINABILITY

Specifications

Color White to Off-white
Target Proteins serine proteases
CAS 329-98-6
Molecular Formula C7H7FO2S
Formula Weight 174.2g/mol
Solubility EtOH, isopropanol, or MeOH
Content And Storage Protect from moisture
Form Crystalline Solid
Quantity 5 g
Purity 99% by GC
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