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MilliporeSigma™ Calbiochem™ (+)-Bicuculline

Catalog No. 5058750001 Shop All MilliporeSigma Products
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50-587-50001 50 mg
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Catalog No. 50-587-50001 Supplier MilliporeSigma™ Supplier No. 5058750001
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Description

A potent allosteric antagonist of vertebrate GABAA recept

A potent allosteric antagonist of vertebrate GABAA receptors. Blocks GABAA-induced chloride currents in cultured neurons (IC50 = 740nM). Shown to increase blood pressure in spontaneously hypertensive rats and cause convulsion in experimental animals. Also, increases the amplitude of spontaneous colonic contractions.
TRUSTED_SUSTAINABILITY

Specifications

Color Pale Yellow
Description 99% by HPLC
Target Proteins GABAA
Molecular Formula C20H17NO6
Solubility DMSO
Content And Storage Protect from light
Form Solid
Quantity 50 mg
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