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MilliporeSigma™ Calbiochem™ (+)-Brefeldin A, Eupenicillium brefeldianum

Catalog No. 2037291MG Shop All MilliporeSigma Products
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20-372-91MG 1 mg
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Catalog No. 20-372-91MG Supplier MilliporeSigma™ Supplier No. 2037291MG
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Description

Specifically and reversibly blocks translocation of proteins from the endoplasmic reticulum (ER) to the Golgi apparatus without affecting endocytosis or lysosome function.

Specifically and reversibly blocks translocation of proteins from the endoplasmic reticulum (ER) to the Golgi apparatus without affecting endocytosis or lysosome function. Inhibitor of HDL-mediated cholesterol efflux. Causes disassembly of the Golgi complex and ER swelling in a variety of mammalian cell lines at <40 ng/ml. Blocks binding of ADP-ribosylation factor to the Golgi and inhibits the GDP-GTP exchange. Inhibits the activity of BIG1 and BIG2, the guanine-nucleotide exchange proteins for ADP-ribosylation factors. Also available as a 25mm solution in DMSO (Cat. No. 500583).
TRUSTED_SUSTAINABILITY

Specifications

Color White
Description 95% by HPLC
Target Proteins Blocks translocation of proteins from the endoplasmic reticulum (ER) to the Golgi apparatus
CAS 20350-15-6
Molecular Formula C16H24O4
Formula Weight 280.4g/mol
Solubility MeOH
Form Crystalline Solid
Quantity 1 mg
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