Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Protein Purification
  5. Protease Inhibitors and Phosphatase Inhibitors
  6. 23212050MG

MilliporeSigma™ Calbiochem™ Cisplatin

Catalog No. 23212050MG
Click to view available options
Quantity:
50 mg

Description

Reported to sensitize glioma cells to TNF-α-induced apoptosis.

A platinum coordination complex with potent anti-neoplastic activity. Induces apoptosis in cancer cells, possibly via caspase-3 activation. Reported to sensitize glioma cells to TNF-α-induced apoptosis.

Note: Athough highly soluble in DMSO, Cisplatin is reported to be rendered inactive due to ligand displacement by the nucleophilic sulfur of DMSO. Sodium chloride solution in water (154mm NaCl with or without 10mg/mL mannitol) or PBS (with 140mm NaCl) is recommended for solubilization prior to culture treatment.
TRUSTED_SUSTAINABILITY

Specifications

Color Yellow
Description 98% by HPLC
Target Proteins Induces apoptosis in cancer cells
CAS 15663-27-1
Molecular Formula Pt(NH3)2Cl2
Formula Weight 300g/mol
Solubility DMSO, H2O with 154 mM NaCl, or PBS with 140 mM NaCl
Form Solid
Quantity 50 mg
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.