Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Protein Purification
  5. Protease Inhibitors and Phosphatase Inhibitors
  6. 2331001MG

MilliporeSigma™ Calbiochem™ CL-387,785

Catalog No. 2331001MG Shop All MilliporeSigma Products
Click to view available options
Quantity:
1 mg

Description

A cell-permeable and irreversible inhibitor of EGF-receptor (EGFR) kinase activity

A cell-permeable and irreversible inhibitor of EGF-receptor (EGFR) kinase activity in vivo (IC50 = 250-490 pM) as well as EGF-stimulated autophosphorylation of tyrosine residues in the EGFR in vivo (IC50 = 5nM). Blocks EGF-mediated growth in A431 cells. Inhibits proliferation of EGFR or c-ErbB2 expressing cells (IC50 = 31-125nM) by covalently binding to the EGFR.
TRUSTED_SUSTAINABILITY

Specifications

Color Pale Yellow
Description 95% by HPLC
Target Proteins EGFR kinase activity
CAS 194423-06-8
Molecular Formula C18H13BrN4O
Formula Weight 381.2g/mol
Solubility DMSO
Content And Storage Hygroscopic, Protect from light
Form Solid
Quantity 1 mg
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.