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MilliporeSigma™ Calbiochem™ Clodronate, Disodium Salt

Catalog No. 23318310MG Shop All MilliporeSigma Products
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23-318-310MG 10 mg
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Description

A non-amino, chloro-containing bisphosphonate that acts as a potent inhibitor of osteoclast-mediated bone resorption.

A non-amino, chloro-containing bisphosphonate that acts as a potent inhibitor of osteoclast-mediated bone resorption. It is metabolized into a non-hydrolyzable ATP analog in osteoclasts and macrophages, and induces apoptosis by inhibiting mitochondrial function. An efficient metal chelator that inhibits invasion, adhesion, and migration of PC-3 prostate cancer cells (IC50 = 100 nM).
TRUSTED_SUSTAINABILITY

Specifications

Color White
Description 97% by titration
Target Proteins Osteoclast-mediated bone resorption
CAS 22560-50-5
Molecular Formula CH2Cl2O6P2Na2·4H2O
Formula Weight 360.9g/mol
Solubility H2O
Content And Storage Hygroscopic
Form Solid
Quantity 10 mg
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