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MilliporeSigma™ Calbiochem™ Cyclo(Arg-Gly-Asp-D-Phe-Val)

Catalog No. 1820151MG Shop All MilliporeSigma Products
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Description

Potent inhibitor of cell adhesion.

Potent inhibitor of cell adhesion. Inhibits tumor cell adhesion to laminin and vitronectin substrates. In vivo investigations in rats showed it to be useful in the amelioration of ischemic acute renal failure in rats. Also inhibits tubular obstruction by preventing cell-cell adhesion. Inhibits the redistribution of c-Src into focal adhesions, thereby leading to impaired MAP Kinase activation.
TRUSTED_SUSTAINABILITY

Specifications

Color White
Formulation Supplied as a trifluoroacetate salt
Description 95% by HPLC
Target Proteins inhibits tumor cell adhesion to laminin and vitronectin substrates
CAS 137813-35-5
Molecular Formula C26H38N8O7
Formula Weight 574.6g/mol
Solubility 1N Acetic Acid
Content And Storage Hygroscopic
Form Solid
Quantity 1 mg
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