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MilliporeSigma™ Calbiochem™ Cyclo(Arg-Gly-Asp-D-Phe-Val)

Potent inhibitor of cell adhesion.

Manufacturer:  MilliporeSigma™ 1820151MG

Catalog No. 18-201-51MG


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Description

Description

Potent inhibitor of cell adhesion. Inhibits tumor cell adhesion to laminin and vitronectin substrates. In vivo investigations in rats showed it to be useful in the amelioration of ischemic acute renal failure in rats. Also inhibits tubular obstruction by preventing cell-cell adhesion. Inhibits the redistribution of c-Src into focal adhesions, thereby leading to impaired MAP Kinase activation.
Specifications

Specifications

Supplied as a trifluoroacetate salt
White solid
1mg
137813-35-5
574.6g/mol
95% by HPLC
Hygroscopic
inhibits tumor cell adhesion to laminin and vitronectin substrates
C26H38N8O7
1N Acetic Acid
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