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MilliporeSigma™ Calbiochem™ Dexamethasone

Most active and highly stable glucocorticoid.

Manufacturer:  MilliporeSigma™ 265005100MG

Catalog No. 26-500-5100MG


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Description

Description

Most active and highly stable glucocorticoid. Causes a reduction in cyclin A and Cdk2 activity, and inhibition of G1/S transition in osteoblasts. Inhibits the phosphorylation of retinoblastoma (Rb) protein. Inhibits the expression of inducible but not constitutive nitric oxide synthase in vascular endothelial cells (IC50 = 5 nM). Enhances active cation transport in aortic smooth muscle cells by stimulating the Na+ - K+ pump. Induces apoptosis in human thymocytes.
Specifications

Specifications

99% by TLC
100mg
50-02-2
392.5g/mol
White solid
Phosphorylation of rb protein
C22H29FO5
DMSO, CHCl3 or EtOH
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