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MilliporeSigma™ Calbiochem™ Flumazenil

Catalog No. 5059910001 Shop All MilliporeSigma Products
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50-599-10001 10 mg
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Catalog No. 50-599-10001 Supplier MilliporeSigma™ Supplier No. 5059910001
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Description

A competitive blocker of benzodiazepine activation of inhibitory GABAergic synpases (ID50 = 200μg/kg/i

A competitive blocker of benzodiazepine activation of inhibitory GABAergic synpases (ID50 = 200μg/kg/i.p). Binds to the benzodiazepine site of GABAA receptors. Enhances GABAA-receptor mediated currents and antagonizes the enhancing effects of benzodiapine agonist flurazepam. Exhibits fast association and dissociation from the benzodiazepine binding site. Permeates the blood brain barrier, however, the level of uptake may depend on efflux effects of p-glycogprotein transporter.
TRUSTED_SUSTAINABILITY

Specifications

Color White
Description 99% by HPLC
Target Proteins GABAA
Molecular Formula C15H14FN3O3
Solubility DMSO
Content And Storage Protect from light
Form Solid
Quantity 10 mg
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