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  6. 38211110MG

MilliporeSigma™ Calbiochem™ Histone Acetyltransferase Inhibitor IV, CPTH2

Catalog No. 38211110MG Shop All MilliporeSigma Products
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Quantity:
10 mg

Description

A cell-permeable thiazolyl-hydrazone compound that inhibits the acetylation of histone H3 by recombinant human Gcn5 in a substrate-competive manner, while exhibiting little activity against rhGcn5 autoacetylation

A cell-permeable thiazolyl-hydrazone compound that inhibits the acetylation of histone H3 by recombinant human Gcn5 in a substrate-competive manner, while exhibiting little activity against rhGcn5 autoacetylation. Although functional knockout of Gcn5 in Saccharomyces cerevisiae by genetic deletion or by CPTH2 treatment is not detrimental to the survival of the budding yeast, CPTH2 treatment is shown to inhibit the growth of yeast strain genetically deleted of Gcn5, but not strains deleted of Elp3 or Sas2.
TRUSTED_SUSTAINABILITY

Specifications

Color Brown
Description 95% by HPLC
CAS 357649-93-5
Molecular Formula C14H14ClN3S
Formula Weight 291.8g/mol
Solubility DMSO
Content And Storage Protect from light
Form Solid
Quantity 10 mg
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