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MilliporeSigma™ Calbiochem™ InSolution™ 5-Aza-2'-Deoxycytidine

Catalog No. 18982610MG Shop All MilliporeSigma Products
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18-982-610MG 10 mg
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Description

A cytosine analog that acts as a DNA methyltransferase inhibitor. Restores caspase-8 and caspase-10 mRNA and protein expression as well as TRAIL (Tumor necrosis factor-Related Apoptosis Inducing Ligand) sensitivity in TRAIL-resistant cell lines.

A cytosine analog that acts as a DNA methyltransferase inhibitor. Restores caspase-8 and caspase-10 mRNA and protein expression as well as TRAIL (Tumor necrosis factor-Related Apoptosis Inducing Ligand) sensitivity in TRAIL-resistant cell lines. Also enhances apoptosis induced by HDAC (Histone Deacetylase) inhibitors. The solid form of this compound (Cat. No. 189825) is also available.
TRUSTED_SUSTAINABILITY

Specifications

Formulation A 100 mM (10mg/438μl) solution of 5-Aza-2′-Deoxycytidine in DMSO.
Description 98% by HPLC
CAS 2353-33-5
Molecular Formula C8H12N4O4
Formula Weight 228.2g/mol
Content And Storage Hygroscopic, Protect from light
Form Liquid
Quantity 10 mg
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