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MilliporeSigma™ Calbiochem™ InSolution™ KN-93
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Quantity:
1 mg
Description
A cell-permeable, competitive inhibitor of Ca2+/calmodulin-dependent protein kinase II (Ki = 370nM). Selectively binds to the Calmodulin (CaM) binding site of the enzyme and prevents the association of CaM with CaM Kinase II. Inhibits glucose-induced and forskolin-stimulated insulin release from isolated pancreatic islets. Has no significant effect on protein kinase A activity. Induces G1 cell cycle arrest and apoptosis in NIH 3T3 cells.

Specifications
Specifications
Formulation | A 5 mM (1mg/399μl) solution of KN-93 in DMSO. |
Description | 95% by HPLC |
Target Proteins | cam kinase 2 |
CAS | 139298-40-1 |
Molecular Formula | C26H29ClN2O4S |
Formula Weight | 501g/mol |
Content And Storage | Hygroscopic, Protect from light |
Form | Liquid |
Quantity | 1 mg |
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