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MilliporeSigma™ Calbiochem™ InSolution™ KN-93

Catalog No. 4227121MG Shop All MilliporeSigma Products
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42-271-21MG 1 mg
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Description

A cell-permeable, competitive inhibitor of Ca2+/calmodulin-dependent protein kinase II (Ki = 370nM)

A cell-permeable, competitive inhibitor of Ca2+/calmodulin-dependent protein kinase II (Ki = 370nM). Selectively binds to the Calmodulin (CaM) binding site of the enzyme and prevents the association of CaM with CaM Kinase II. Inhibits glucose-induced and forskolin-stimulated insulin release from isolated pancreatic islets. Has no significant effect on protein kinase A activity. Induces G1 cell cycle arrest and apoptosis in NIH 3T3 cells.
TRUSTED_SUSTAINABILITY

Specifications

Formulation A 5 mM (1mg/399μl) solution of KN-93 in DMSO.
Description 95% by HPLC
Target Proteins cam kinase 2
CAS 139298-40-1
Molecular Formula C26H29ClN2O4S
Formula Weight 501g/mol
Content And Storage Hygroscopic, Protect from light
Form Liquid
Quantity 1 mg
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