Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Protein Purification
  5. Protease Inhibitors and Phosphatase Inhibitors
  6. 475821250UG

MilliporeSigma™ Calbiochem™ InSolution™ Microcystin-LR, Microcystis aeruginosa

Catalog No. 475821250UG Shop All MilliporeSigma Products
Change view
Click to view available options
Quantity:
250 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
47-582-1250UG 250 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. 47-582-1250UG Supplier MilliporeSigma™ Supplier No. 475821250UG
Only null left
Add to Cart
Add to Cart

Description

Cyclic heptapeptide toxin isolated from the freshwater cyanobacteria, Microcystis aeruginosa

Cyclic heptapeptide toxin isolated from the freshwater cyanobacteria, Microcystis aeruginosa . Potent inhibitor of protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A). Unlike Okadaic Acid (Cat. No. 495604), microcystin-LR is effective on both PP1 (IC50 = 1.7nM) and PP2A (IC50 = 40 pM). Reacts with phosphatase in a two-step mechanism involving rapid binding and inactivation of the catalytic subunit followed by slower covalent interactions. Has no effect on protein kinases, making it useful for reducing contaminating phosphatase activities in protein kinase assays.
TRUSTED_SUSTAINABILITY

Specifications

Formulation A 2.5 mM (250μg/100μl) solution of Microcystin-LR, Microcystis aeruginosa in DMSO.
Description 95% by HPLC
Target Proteins protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A)
Molecular Formula C49H74N10O12
Formula Weight 995.2g/mol
Content And Storage Hygroscopic, Protect from light
Form Liquid
Quantity 250 μg
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.