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MilliporeSigma™ Calbiochem™ InSolution™ OM99-2

Catalog No. 496000250UG Shop All MilliporeSigma Products
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49-600-0250UG 250 μg
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Catalog No. 49-600-0250UG Supplier MilliporeSigma™ Supplier No. 496000250UG
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Description

An eight residue peptidomimetic, tight binding transition-state analog inhibitor of human brain memapsin 2.

An eight residue peptidomimetic, tight binding transition-state analog inhibitor of human brain memapsin 2 (Ki = 1.6 nM, recombinant memapsin 2; Ki = 9.58 nM, recombinant pro-memapsin 2). Also inhibits cathepsin D (Ki = 48nM). This aspartyl protease inhibitor is designed from the template of the β-secretase site of Swedish β-amyloid precursor protein (APP) with Asp to Ala replacement; also includes a nonhydrolyzable hydroxyethylene isostere between Leu and Ala.
TRUSTED_SUSTAINABILITY

Specifications

Formulation A 1 mM (250μg in 280μl) solution in DMSO. Supplied as a trifluoroacetate salt.
Description 90% by HPLC
Target Proteins human brain memapsin 2
Molecular Formula C41H64N8O14
Formula Weight 893g/mol
Content And Storage Protect from Light, Protect from Moisture
Form Liquid
Quantity 250 μg
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