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MilliporeSigma™ Calbiochem™ InSolution™ OM99-2 Available on GSA/VA Contract for Federal Government customers only.

An eight residue peptidomimetic, tight binding transition-state analog inhibitor of human brain memapsin 2.

Manufacturer:  MilliporeSigma™ 496000250UG

Catalog No. 49-600-0250UG


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Description

Description

An eight residue peptidomimetic, tight binding transition-state analog inhibitor of human brain memapsin 2 (Ki = 1.6 nM, recombinant memapsin 2; Ki = 9.58 nM, recombinant pro-memapsin 2). Also inhibits cathepsin D (Ki = 48nM). This aspartyl protease inhibitor is designed from the template of the β-secretase site of Swedish β-amyloid precursor protein (APP) with Asp to Ala replacement; also includes a nonhydrolyzable hydroxyethylene isostere between Leu and Ala.

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Specifications

Specifications

A 1 mM (250μg in 280μl) solution in DMSO. Supplied as a trifluoroacetate salt.
Liquid
250μg
C41H64N8O14
90% by HPLC
Protect from Light
Protect from Moisture
human brain memapsin 2
893g/mol
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