MilliporeSigma™ Calbiochem™ InSolution™ Phorbol-12-myristate-13-acetate
Most commonly-used phorbol ester
Supplier: MilliporeSigma™ 5.00582.0001
DescriptionMost commonly-used phorbol ester. Extremely potent mouse skin tumor promoter. Activates protein kinase C in vivo and in vitro , even atnM concentrations. Promotes the expression of iNOS in cultured hepatocytes. Activates Ca2+-ATPase and potentiates forskolin (Cat. No. 344270, Cat. No. 344282)-induced cAMP formation. Inhibits apoptosis induced by the Fas antigen, but induces apoptosis in HL-60 promyelocytic leukemia cells. Its binding is reversible.
|A 10 mM (2mg/324μL) solution of Phorbol-12-myristate-13-acetate in DMSO.|
|98% by HPLC|
|Avoid Freeze-Thaw Cycles, Hygroscopic, Protect from Light|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok