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MilliporeSigma™ Calbiochem™ InSolution™ Phorbol-12-myristate-13-acetate

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2mg
Description
Most commonly-used phorbol ester. Extremely potent mouse skin tumor promoter. Activates protein kinase C in vivo and in vitro , even atnM concentrations. Promotes the expression of iNOS in cultured hepatocytes. Activates Ca2+-ATPase and potentiates forskolin (Cat. No. 344270, Cat. No. 344282)-induced cAMP formation. Inhibits apoptosis induced by the Fas antigen, but induces apoptosis in HL-60 promyelocytic leukemia cells. Its binding is reversible.
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Specifications
Specifications
Formulation | A 10 mM (2mg/324μL) solution of Phorbol-12-myristate-13-acetate in DMSO. |
Description | 98% by HPLC |
Target Proteins | PKC |
Molecular Formula | C36H56O8 |
Formula Weight | 616.8g/mol |
Content And Storage | Avoid Freeze-Thaw Cycles, Hygroscopic, Protect from Light |
Form | Liquid |
Quantity | 2 mg |
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