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MilliporeSigma™ Calbiochem™ InSolution™ SB 202190
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Quantity:
1 mL
Description
A potent and cell-permeable inhibitor of p38 MAP kinase. Inhibits p38 phosphorylation of myelin basic protein (MBP) with no effect on the activity of the ERK or JNK MAP kinase subgroups. Also inhibits the kinase activity of p38β (IC50 = 350nM) and p38 phosphorylation of activating transcription factor 2 (ATF-2; IC50 = 280nM). Blocks LPS-induced TNF-α and interleukin biosynthesis. Reported to block LDL expression in Hep52 cells.

Specifications
Specifications
Formulation | A 1mg/mL solution of SB 202190 in anhydrous DMSO. |
Description | 98% by HPLC |
Target Proteins | P38β |
CAS | 152121-30-7 |
Molecular Formula | C20H14FN3O |
Formula Weight | 331.1g/mol |
Content And Storage | Protect from light |
Form | Liquid |
Quantity | 1 mL |
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