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  6. 572631500UG

MilliporeSigma™ Calbiochem™ InSolution™ SU5402

Catalog No. 572631500UG Shop All MilliporeSigma Products
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Quantity:
500 μg

Description

Inhibits the tyrosine kinase activity of FGFR1 (IC50 = 10-20μM in the presence of 1mm ATP) by interacting with the catalytic domain of FGFR1

Inhibits the tyrosine kinase activity of FGFR1 (IC50 = 10-20μM in the presence of 1mm ATP) by interacting with the catalytic domain of FGFR1. Also inhibits aFGF-induced phosphorylation of ERK1 and ERK2 (IC50 = 10-20μM). In contrast to SU4984, it acts only as a weak inhibitor of tyrosine phosphorylation of the PDGF receptor. Does not inhibit the phosphorylation of insulin receptor and exhibits no inhibitory effect on EGF receptor kinase.
TRUSTED_SUSTAINABILITY

Specifications

Formulation A 10 mM (500μg/169μl) solution of SU5402 in DMSO.
Description 95% by HPLC
Molecular Formula C17H16N2O3
Formula Weight 296.3g/mol
Content And Storage Hygroscopic, Protect from light
Form Liquid
Quantity 500 μg
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