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MilliporeSigma™ Calbiochem™ InSolution™ SU6656

Catalog No. 572636500UG Shop All MilliporeSigma Products
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57-263-6500UG 500 μg
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Catalog No. 57-263-6500UG Supplier MilliporeSigma™ Supplier No. 572636500UG
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Description

A potent inhibitor of Src-family protein tyrosine kinases

A potent inhibitor of Src-family protein tyrosine kinases. Inhibits Src (IC50 = 280nM) as well as closely related kinases Fyn (IC50 = 170nM), Yes (IC50 = 20nM) and Lyn (IC50 = 130nM). The inhibition is competitive with respect to ATP. Has only a trivial effect on Lck (IC50 = 6.88μM). Does not affect the activity of PDGF-β receptor kinase (IC50 >10μM) and IGF-1 receptor kinase (IC50 gt;20μM).
TRUSTED_SUSTAINABILITY

Specifications

Formulation A 10 mM (500μg/135μl) solution of SU6656 in DMSO.
Description 95% by HPLC
Target Proteins Src
Molecular Formula C19H21N3O3S
Formula Weight 371.5g/mol
Content And Storage Hygroscopic, Protect from light
Form Liquid
Quantity 500 μg
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