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MilliporeSigma™ Calbiochem™ InSolution™ Trichostatin A, Streptomyces sp.

Catalog No. 647926500UG Shop All MilliporeSigma Products
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64-792-6500UG 500 μg
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Description

A potent and reversible inhibitor of histone deacetylase

A potent and reversible inhibitor of histone deacetylase. Blocks cell cycle progression at the G1 phase in HeLa cells and induces a 12-fold increase in intracellular levels of gelsolin. Induces reversion of oncogenic ras-tranformed NIH 3T3 cells to a normal morphology. Inhibits IL-2 gene expression (IC50 = 73nM) in Jurkat cells and shows immunosuppressive activity in a mouse model.
TRUSTED_SUSTAINABILITY

Specifications

Formulation A 10 mM (500μg/165μl) solution of Trichostatin A, Streptomyces sp. in DMSO.
Description 98% by HPLC
Target Proteins histone deactylase
Molecular Formula C17H22N2O3
Formula Weight 302.4g/mol
Content And Storage Hygroscopic, Protect from light
Form Liquid
Quantity 500 μg
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