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MilliporeSigma™ Calbiochem™ KB-R7943

Catalog No. 4203365MG Shop All MilliporeSigma Products
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42-033-65MG 5 mg
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Description

A cell-permeable isothiourea derivative that inhibits the influx/reverse mode of Na+/Ca2+ exchangers (NCX; IC50

A cell-permeable isothiourea derivative that inhibits the influx/reverse mode of Na+/Ca2+ exchangers (NCX; IC50 = 4.3μM, 4.7μM, and 1.4μM for NCX1,NCX2, and NCX3, respectively) and directly modulates Na+/Mg2+ exchange in a Ca2+-dependent manner. Reported to offer neuronal and cardioprotection. Also inhibits nicotinic acetylcholine receptors and NMDA receptor channels (IC50 < 10μM).
TRUSTED_SUSTAINABILITY

Specifications

Color White
Description 98% by HPLC
Target Proteins Na+/Ca2+ exchangers
CAS 182004-65-5
Molecular Formula C16H17N3O3S·MeSO3H
Formula Weight 427.5g/mol
Solubility DMSO or H2O
Content And Storage Hygroscopic, Protect from light
Form Crystalline Solid
Quantity 5 mg
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