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MilliporeSigma™ Calbiochem™ α,β-methylene ATP
A metabolically stable and selective P2X purinergic receptor agonist (pEC50
Supplier: MilliporeSigma™ 5.05419.0001
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DescriptionA metabolically stable and selective P2X purinergic receptor agonist (pEC50 = 5.81) that is shown to be more potent than ATP. Elicits contractions in ileum through the release of endogenous acetylcholine, which can be blocked by tetrodotoxin (∽1 mM). Shown to depolarize cells of the longitudinal muscle strips (∽ 200nM to 4μM) that reaches a peak within 2-3 min after application and then decays to a steady level.
|Hygroscopic, Protect from light|
|98% by HPLC|
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