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MilliporeSigma™ Calbiochem™ α,β-methylene ATP
A metabolically stable and selective P2X purinergic receptor agonist (pEC50
Supplier: MilliporeSigma™ 5.05419.0001
Description
A metabolically stable and selective P2X purinergic receptor agonist (pEC50 = 5.81) that is shown to be more potent than ATP. Elicits contractions in ileum through the release of endogenous acetylcholine, which can be blocked by tetrodotoxin (∽1 mM). Shown to depolarize cells of the longitudinal muscle strips (∽ 200nM to 4μM) that reaches a peak within 2-3 min after application and then decays to a steady level.Specifications
Hygroscopic, Protect from light | |
Powder | |
98% by HPLC | |
C11H18N5O12P3·xLi+ |
5 mg | |
White | |
P2X | |
H2O |
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