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MilliporeSigma™ Calbiochem™ Myriocin, Mycelia sterilia

A potent immunosuppressant.

Supplier:  MilliporeSigma™ 4763005MG

Catalog No. 47-630-05MG


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Description

Description

A potent immunosuppressant. Displays 10- to 100-fold more potent immunosuppressant activity than cyclosporin A. Potently inhibits serine palmitoyltransferase (SPT; Ki = 280 pM) thereby blocking the synthesis of ceramide. Disrupts substratum adhesion of melanoma cells. Inhibits cell proliferation and induces apoptosis in IL-2 dependent murine cytotoxic T lymphocyte cell line CTLL-2.
Specifications

Specifications

White
Serine palmitoyltransferase
C21H39NO6
DMSO
5 mg
95% by TLC
35891-70-4
401.5g/mol
Solid
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SDS
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