MilliporeSigma™ Calbiochem™ Myriocin, Mycelia sterilia
A potent immunosuppressant.
Supplier: MilliporeSigma™ 4763005MG
DescriptionA potent immunosuppressant. Displays 10- to 100-fold more potent immunosuppressant activity than cyclosporin A. Potently inhibits serine palmitoyltransferase (SPT; Ki = 280 pM) thereby blocking the synthesis of ceramide. Disrupts substratum adhesion of melanoma cells. Inhibits cell proliferation and induces apoptosis in IL-2 dependent murine cytotoxic T lymphocyte cell line CTLL-2.
|95% by TLC
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