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MilliporeSigma™ Calbiochem™ N-Ethylmaleimide

Sulfhydryl alkylating reagent that inhibits H+-ATPase and suppresses the short circuit current (IC50 = 22 μM) in pancreatic duct cells.

Supplier:  MilliporeSigma™ 341155GM

Catalog No. 34-115-5GM


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Description

Description

Sulfhydryl alkylating reagent that inhibits H+-ATPase and suppresses the short circuit current (IC50 = 22μM) in pancreatic duct cells. Inactivates NADP-dependent isocitrate dehydrogenase. Also a potent inhibitor of both Mg2+ and Ca2+/Mg2+-stimulated DNA fragmentation in rat liver nuclei. Stimulates arachidonic acid release through activation of PLA2 in endothelial cells.
Specifications

Specifications

White
H+-ATPase
C6H7NO2
EtOH
5 g
98% by HPLC
128-53-0
125.1g/mol
Solid
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