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MilliporeSigma™ Calbiochem™ Nefazodone Hydrochloride

Catalog No. 5081480001 Shop All MilliporeSigma Products
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10mg

Description

A potent 5-HT2A receptor antagonist (Kd = 26nM), with moderate affinity for the alpha1-adrenergic receptor (Kd = 48nM) and 5-HT1A receptor

A potent 5-HT2A receptor antagonist (Kd = 26nM), with moderate affinity for the alpha1-adrenergic receptor (Kd = 48nM) and 5-HT1A receptor (Kd = 80nM). Originally developed as a clinical antidepressant but discontinued in 2004, nefazodone (Serzone) still remains a specific inhibitor of certain serotonergic pathways. Nefazodone also has been reported to induce mitochondrial dysfuntion.
TRUSTED_SUSTAINABILITY

Specifications

Color White
Description 99% by HPLC
Target Proteins 5-HT2A
Molecular Formula C25H32ClN5O2·HCl
Solubility DMSO or EtOH
Content And Storage Protect from light
Form Solid
Quantity 10 mg
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