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MilliporeSigma™ Calbiochem™ PD 153035
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Quantity:
1 mg
Description
An extremely potent, cell-permeamble, reversible, ATP-competitive and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC50 = 25 pM; Ki = 6 pM). Rapidly suppresses autophosphorylation of EGFR at low nanomolar concentrations in fibroblasts or in human epidermoid carcinoma cells. Also selectively blocks EGF-mediated cellular processes including mitogenesis, early gene expression, and oncogenic transformation. A 10mm (500μg/139μl) solution of PD 153035 (Cat. No. 234491) in DMSO is also available.

Specifications
Specifications
Color | White |
Description | 97% by HPLC |
Target Proteins | EGFR |
CAS | 153436-54-5 |
Molecular Formula | C16H14BrN3O2 |
Formula Weight | 360.2g/mol |
Solubility | DMSO |
Content And Storage | Protect from light |
Form | Solid |
Quantity | 1 mg |
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