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MilliporeSigma™ Calbiochem™ Plasminogen Activator Inhibitor-1, Human, Recombinant
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Quantity:
50 μg
Description
PAI-1 is the primary inhibitor of both tissue plasminogen activator (tPA) and urokinase (uPA). PAI-1 can exist either in an active inhibitory conformation or in an inactive or latent conformation. This highly purified preparation has not been exposed to denaturing conditions and has been chromatographically purified of latent material. PAI-1 is a marker for acute myocardial infarction and several thrombolytic disorders. Protects platelets against the inhibitory effects of plasma. Reported to be an important prognostic factor in breast cancer patients. PAI-1 is highly stable when stored at or below pH 6.6.

Specifications
Specifications
Formulation | In 150 mM NaCl, 50 mM sodium phosphate buffer, 1 mM EDTA, pH 6.6. |
Description | 98% by SDS-PAGE |
Target Proteins | Tissue plasminogen activator (tPA) and urokinase (uPA) |
Formula Weight | 43000g/mol |
Content And Storage | Avoid Freeze-Thaw Cycles |
Form | Liquid |
Quantity | 50 μg |
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