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MilliporeSigma™ Calbiochem™ Plasminogen Activator Inhibitor-1, Human, Recombinant

Catalog No. 52820550UG Shop All MilliporeSigma Products
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52-820-550UG 50 μg
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Catalog No. 52-820-550UG Supplier MilliporeSigma™ Supplier No. 52820550UG
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Description

Primarily used for Protease Inhibitors applications.

PAI-1 is the primary inhibitor of both tissue plasminogen activator (tPA) and urokinase (uPA). PAI-1 can exist either in an active inhibitory conformation or in an inactive or latent conformation. This highly purified preparation has not been exposed to denaturing conditions and has been chromatographically purified of latent material. PAI-1 is a marker for acute myocardial infarction and several thrombolytic disorders. Protects platelets against the inhibitory effects of plasma. Reported to be an important prognostic factor in breast cancer patients. PAI-1 is highly stable when stored at or below pH 6.6.
TRUSTED_SUSTAINABILITY

Specifications

Formulation In 150 mM NaCl, 50 mM sodium phosphate buffer, 1 mM EDTA, pH 6.6.
Description 98% by SDS-PAGE
Target Proteins Tissue plasminogen activator (tPA) and urokinase (uPA)
Formula Weight 43000g/mol
Content And Storage Avoid Freeze-Thaw Cycles
Form Liquid
Quantity 50 μg
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