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MilliporeSigma™ Calbiochem™ Platelet Membrane Glycoproteins, IIbIIIa, Human Platelets
Shop All MilliporeSigma ProductsDescription
- Platelet integrin that binds to fibrinogen via recognition sequence Arg-Gly-Asp-Ser
- Acts as receptor for such adhesive ligands as fibrinogen, fibronectin and von Willebrand factor during platelet stimulation
- Glycoproteins IIb and IIIa constitute fibrinogen receptor
- Required for platelet aggregation
- Glycoprotein IIb consists of two disulfide-linked subunits, GPIIbα, and GPIIbβ, whereas GPIIIa has only one polypeptide chain
Specifications
Specifications
| Formulation | In 100mM NaCl, 20mM Tris-HCl, 1mM CaCl2, 50% glycerol, 0.1% TRITON™ X-100 Detergent, ≤0.1% sodium azide, pH 7.4 |
| Quantity | 1 mg |
| Source | Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. |
| Storage Requirements | ≤ -70°C |
| Form | Liquid |
For Research Use Only
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