Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Protein Purification
  5. Protease Inhibitors and Phosphatase Inhibitors
  6. 52959910MG

MilliporeSigma™ Calbiochem™ PP1 Analog V, 2,3-DMB-PP1

Catalog No. 52959910MG
Click to view available options
Quantity:
10 mg

Description

A cell-permeable 3-MB-PP1 analog that is more effective than 3-MB-PP1 in inhibiting Syk

A cell-permeable 3-MB-PP1 (Cat. No. 529582) analog that is more effective than 3-MB-PP1 in inhibiting SykM442A S505A ASKA- (analog-sensitive kinase alleles) mediated cellular calcium flux (98% vs. 20% inhibition, respectively, by 1μM 2,3-DMB-PP1 or 3-MB-PP1) in Syk MASA-expressing DT40 cells. Also shown to selectively inhibit L159G ASKA, but not wt, PDK1-dependent GSK3andalpha Ser21 and S6 Ser235/236 phosphorylation upon IGF1 stimulation in mES cells.
TRUSTED_SUSTAINABILITY

Specifications

Color Off-white
Description 97% by HPLC
CAS 956026-24-7
Molecular Formula C18H23N5
Formula Weight 309.4g/mol
Solubility DMSO
Content And Storage Protect from light
Form Powder
Quantity 10 mg
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.