Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Life Sciences
  4. Protein Biology
  5. Protein Extraction and Purification
  6. Protein Purification
  7. Protease Inhibitors and Phosphatase Inhibitors
  8. 5593881MG

MilliporeSigma™ Calbiochem™ SB 202190

SB 202190, CAS 152121-30-7, is a potent, reversible, competitive inhibitor of p38. Inhibits p38 phosphorylation of myelin basic protein. Blocks the activity of p38β (K

Manufacturer:  MilliporeSigma™ 5593881MG

Catalog No. 55-938-81MG


Add to cart

Description

Description

A potent, reversible, competitive, and cell-permeable inhibitor of p38 MAP kinase. Inhibits p38 phosphorylation of myelin basic protein (MBP) with no effect on the activity of the ERK or JNK MAP kinase subgroups. Also inhibits the kinase activity of p38β (Ki = 16nM; IC50 = 350nM) and p38 phosphorylation of activating transcription factor 2 (ATF-2; IC50 = 280nM). Blocks LPS-induced TNF-α and interleukin biosynthesis. Reported to induce LDL receptor expression in Hep52 cells. A 1mg/mL solution of SB 202190 (Cat. No. 559397) in anhydrous DMSO is also available.
Specifications

Specifications

98% by HPLC
Protect from Light
p38β
C20H14FN3O
DMSO
Pale yellow solid
1mg
152121-30-7
331.3g/mol
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit