Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
MilliporeSigma™ Calbiochem™ SB 202190
Click to view available options
Quantity:
1 mg
Description
A potent, reversible, competitive, and cell-permeable inhibitor of p38 MAP kinase. Inhibits p38 phosphorylation of myelin basic protein (MBP) with no effect on the activity of the ERK or JNK MAP kinase subgroups. Also inhibits the kinase activity of p38β (Ki = 16nM; IC50 = 350nM) and p38 phosphorylation of activating transcription factor 2 (ATF-2; IC50 = 280nM). Blocks LPS-induced TNF-α and interleukin biosynthesis. Reported to induce LDL receptor expression in Hep52 cells. A 1mg/mL solution of SB 202190 (Cat. No. 559397) in anhydrous DMSO is also available.

Specifications
Specifications
Color | Pale Yellow |
Description | 98% by HPLC |
Target Proteins | p38β |
CAS | 152121-30-7 |
Molecular Formula | C20H14FN3O |
Formula Weight | 331.3g/mol |
Solubility | DMSO |
Content And Storage | Protect from light |
Form | Solid |
Quantity | 1 mg |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction