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MilliporeSigma™ Calbiochem™ SB-277011-A Dihydrochloride

Catalog No. 5054840001 Shop All MilliporeSigma Products
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50-548-40001 5 mg
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Catalog No. 50-548-40001 Supplier MilliporeSigma™ Supplier No. 5054840001
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Description

A brain-penetrant, high-affinity, and selective dopamine D3 receptor antagonist

A brain-penetrant, high-affinity, and selective dopamine D3 receptor antagonist. High affinity for the hD3 receptor (pKi = 7.95) with 100-fold selectivity over the hD2 receptor and over 66 other receptors, enzymes, and ion channels. Rat data shows that the compound is selective for the D3 receptor over certain serotonergic and cholinergic receptors at doses up to 56.0mg/kg and strong physiological response at 32.0mg/kg.
TRUSTED_SUSTAINABILITY

Specifications

Color White
Description 98% by HPLC
Target Proteins D3
Molecular Formula C28H30N4O·2HCl
Solubility H2O
Content And Storage Hygroscopic, Protect from light
Form Solid
Quantity 5 mg
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