Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Protein Purification
  5. Protease Inhibitors and Phosphatase Inhibitors
  6. 5657581MG

MilliporeSigma™ Calbiochem™ β-Secretase Substrate IV, Fluorogenic

Catalog No. 5657581MG Shop All MilliporeSigma Products
Click to view available options
Quantity:
1 mg

Description

β-Secretase Substrate IV, Fluorogenic, is a highly sensitive FRET substrate. Hydrolysis of the substrate (Leu-Asp cleavage) by β-secretase results in fluorescence enhancement.

A highly sensitive fluorescence resonance energy transfer (FRET) peptide substrate, based on the EVNLDAEF sequence derived from the β-secretase site of the Swedish mutation of Amyloid Precursor Protein (APP). Hydrolysis of the substrate (Leu-Asp cleavage) by β-secretase results in fluorescence enhancement. kcat/Km values (min-1/μM) at 37°C, pH 4.5, for pro-memapsin 2 and its activated species Leu28p-memapsin 2 are 0.044 and 0.040, respectively.
TRUSTED_SUSTAINABILITY

Specifications

Color Red
Formulation Supplied as a trifluoroacetate salt.
Description 95% by HPLC
Target Proteins β-secretase substrate
Molecular Formula C91H129N25O25S
Formula Weight 2005.2g/mol
Solubility DMSO
Content And Storage Protect from light
Form Lyophilized
Quantity 1 mg
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.