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MilliporeSigma™ Calbiochem™ STAT5 Inhibitor II, IQDMA

Catalog No. 42029410MG Shop All MilliporeSigma Products
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42-029-410MG 10 mg
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Description

The STAT5 Inhibitor II, IQDMA controls the biological activity of STAT5.

A cell-permeable indoloquinoline compound that exhibits anticancer activity and inhibits the growth of A549 lung cancer cells (IC50 = 8μM), as well as HL-60 (IC50 = 5μM) and K562 (IC50 = 8μM) leukemia cells. IQDMA-mediated apoptosis is shown to correlate with a downregulation of STAT5 pathway signaling in HL-60 and K562 cultures, while JNK and p38 signalings are shown to be activated in A549 cells upon IQDMA treatment.
TRUSTED_SUSTAINABILITY

Specifications

Color Brown
Description 95% by HPLC
Molecular Formula C19H20N4
Formula Weight 304.39g/mol
Solubility DMSO
Form Solid
Quantity 10 mg
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