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MilliporeSigma™ Calbiochem™ Nα-Tosyl-Lys Chloromethyl Ketone, Hydrochloride
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Quantity:
50 mg
250 mg
Description
Inhibits trypsin-like serine proteinases. Irreversibly inactivates trypsin without affecting chymotrypsin. Prevents nitric oxide production by activated macrophages by interfering with transcription of the iNOS gene. Blocks cell-cell adhesion and binding of HIV-1 virus to the target cells. In macrophages, blocks nitric oxide synthase induced by interferon-γ and lipopolysaccharides (EC50 = 80μM). Prevents endonucleolysis accompanying apoptotic death of HL-60 leukemia cells and normal thymocytes.

Specifications
Specifications
Color | Off-white |
Target Proteins | trypsin like proteases |
CAS | 4238-41-9 |
Molecular Formula | C14H21ClN2O3S·HCl |
Formula Weight | 369.3g/mol |
Solubility | Aqueous solutions (unstable above pH 6.0) |
Content And Storage | Hygroscopic |
Form | Solid |
Quantity | 50 mg |
Purity | 95% by elemental analysis |
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