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MilliporeSigma™ Calbiochem™ Sumanirole Maleate

Catalog No. 5058960001 Shop All MilliporeSigma Products
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50-589-60001 5 mg
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Catalog No. 50-589-60001 Supplier MilliporeSigma™ Supplier No. 5058960001
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Description

An extremely selective dopamine D2 receptor agonist (Ki =

An extremely selective dopamine D2 receptor agonist (Ki = 9nM). Commonly used in Parkinson′s Disease models and to reproduce cocaine′s discriminative stimulus effects. Sumanirole has greater than 200-fold selectivity for the D2 receptor subtype versus the other dopamine receptor subtypes in radioligand binding assays. In cell-based assays, sumanirole is a fully efficacious agonist, with EC50 values between 17 and 75 nM. In animals, sumanirole elicits many physiological responses attributed to D2-like receptor function.
TRUSTED_SUSTAINABILITY

Specifications

Color Off-white
Description 98% by HPLC
Target Proteins D2
Molecular Formula C11H13N3O·C4H4O4
Solubility DMSO
Content And Storage Protect from light
Form Solid
Quantity 5 mg
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