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MilliporeSigma™ Calbiochem™ T0901317

Catalog No. 57531010MG Shop All MilliporeSigma Products
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57-531-010MG 10 mg
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Description

A cell-permeable, nonsterol, benzenesulfonamide compound that acts as a highly selective and potent liver X receptor agonist (EC50 of 20nM for LXRα

A cell-permeable, nonsterol, benzenesulfonamide compound that acts as a highly selective and potent liver X receptor agonist (EC50 of 20nM for LXRα). Reported to induce the expression of genes associated with fatty acid biosynthesis and raise both the levels of serum HDL cholesterol and triglyceride in mice. Also reduces the development of atherosclerosis in LDL receptor-deficient mice and lowers plasma glucose in diabetic rodents.
TRUSTED_SUSTAINABILITY

Specifications

Color Light Beige
Description 98% by HPLC
Target Proteins Liver X receptor (LXRα)
CAS 293754-55-9
Molecular Formula C17H12NSO3F9
Formula Weight 481.3g/mol
Solubility DMSO or EtOH
Content And Storage Protect from light
Form Solid
Quantity 10 mg
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